References
1. CDC. The health consequences of smoking: a report of the Surgeon General. Atlanta, GA: US Department of Health and Human Services, CDC; 2004.
2. World Health Organization, The World Health Report 1999, Making a Difference, Chapter 5: Combating the Tobacco Epidemic, World Health Report, Geneva, Switzerland 1999.
3. Centers for Disease Control and Prevention, Reducing Tobacco Use: A Report of the Surgeon General, US Department of Health and Human Services, CDC, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health, 2000.
4. U.S. Department of Health and Human Services, Healthy People 2010 (2nd ed.), Chapter 27, Tobacco Use, Washington, D.C.: U.S. Government Printing Office, November 2000.
5. Centers for Disease Control and Prevention (CDC), Annual Smoking�Attributable Mortality, Years of Potential Life Lost, and Productivity Losses � United States, 1997�2001, MMWR 2005; 54: 625-8.
6. World Health Organization, The World Health Report 2002, Reducing Risks, Promoting Healthy Life, Chapter 4: Quantifying Selected Major Risks to Health, World Health Report, Geneva, Switzerland 2002.
7. Woehlck HJ, Connolly LA, Cinquegrani MP, Dunning MB III, Hoffmann RG: Acute smoking increases ST depression in humans during general anesthesia. Anesth Analg 1999; 89:856�60.
8. Svensson LG, Hess KR, Coselli JS, Safi HJ, Crawford ES: A prospective study of respiratory failure after high-risk surgery on the thoracoabdominal aorta. J Vasc Surg 1991; 14:271�82.
9. Moller AM, Maaloe R, Pedersen T: Postoperative intensive care admit�tance: The role of tobacco smoking. Acta 106. Anaesthesiol Scand 2001; 45:345�8.
10. Dilworth JP, White RJ: Postoperative chest infection after upper abdom�inal surgery: An important problem for smokers. Respir Med 1992; 86:205�10.
11. Dennis A, Curran J, Sherriff J, Kinnear W: Effects of passive and active smoking on induction of anaesthesia. BrJ Anaesth 1994; 73:450�2.
12. Warner MA, Divertie MB, Tinker JH: Preoperative cessation of smoking and pulmonary complications in coronary artery bypass patients. ANESTHESIOLOGY 1984; 60:380�3.
13. Warner MA, Offord KP, Warner ME, Lennon RL, Conover MA, Jansson-Schumacher U: Role of preoperative cessation of smoking and other factors in postoperative pulmonary complications: A blinded prospective study of coronary artery bypass patients. Mayo Clin Proc 1989; 64:609�16.
14. Myles PS, Iacono GA, HuntJO, Fletcher H, MorrisJ, McIlroy D, Fritschi L: Risk of respiratory complications and wound infection in patients undergoing ambulatory surgery: Smokers versus nonsmokers. ANESTHESIOLOGY 2002; 97:842�7.
15. Fawcett A, Shembekar M, ChurchJS, Vashisht R, Springall RG, Nott DM: Smoking, hypertension, and colonic anastomotic healing; a combined clinical and histopathological study. Gut 1996; 38:714�8
16. Chang LD, Buncke G, Slezak S, Buncke HJ: Cigarette smoking, plastic surgery, and microsurgery. J Reconstr Microsurg 1996; 12:467�74.
17. Moller AM, Pedersen T, Villebro N, Munksgaard A: Effect of smoking on early complications after elective orthopaedic surgery. J Bone Joint Surg Br 2003; 85: 178�81.
18. Moller AM, Villebro N, Pedersen T, Tonnesen H: Effect of preoperative smoking intervention on postoperative complications: A randomised clinical trial. Lancet 2002; 359:114�7.
19. Sorensen LT, HorbyJ, Friis E, Pilsgaard B, Jorgensen T: Smoking as a risk factor for wound healing and infection in breast cancer surgery. EurJ Surg Oncol 2002; 28:815�20.
20. Silverstein P: Smoking and wound healing. Am J Med 1992; 93:22S�4S.
21. Arnez ZM, Bajec J, Bardsley AF, Scamp T, Webster MH: Experience with 50 free TRAM flap breast reconstructions. Plast Reconstr Surg 1991; 87:470�8.
22. Goldminz D, Bennett RG: Cigarette smoking and flap and full-thickness graft necrosis. Arch Dermatol 1991; 127:1012�5.
23. Kurz A, Sessler DI, Lenhardt R: Perioperative normothermia to reduce the incidence of surgical-wound infection and shorten hospitalization. Study of Wound Infection and Temperature Group. N EnglJ Med 1996; 334:1209�15.
24. Greif R, Akca O, Horn EP, Kurz A, Sessler DI: Supplemental perioperative oxygen to reduce the incidence of surgical-wound infection. N EnglJ Med 2000; 342: 161�7.
25. Glassman SD, Anagnost SC, ParkerA, Burke D,JohnsonJR, DimarJR: The effect of cigarette smoking and smoking cessation on spinal fusion. Spine 2000; 25:2608�15.
26. Hadley MN, Reddy SV: Smoking and the human vertebral column: A review of the impact of cigarette use on vertebral bone metabolism and spinal fusion. Neurosurgery 1997; 41:116�24.
27. Andersen T, Christensen FB, Laursen M, Hoy K, Hansen ES, Bunger C: Smoking as a predictor of negative outcome in lumbar spinal fusion. Spine 2001; 26:2623�8.
28. Martin GJJr, Haid RWJr, MacMillan M, Rodts GEJr, Berkman R: Anterior cervical discectomy with freeze-dried fibula allograft: Overview of 317 cases and literature review. Spine 1999; 24:852�8.
29. Deguchi M, Rapoff AJ, Zdeblick TA: Posterolateral fusion for isthmic spondylolisthesis in adults: Analysis of fusion rate and clinical results. J Spinal Disord 1998; 11:459�64.
30. Bishop RC, Moore KA, Hadley MN: Anterior cervical interbody fusion using autogeneic and allogeneic bone graft substrate: A prospective comparative analysis. J Neurosurg 1996; 85:206�10.
31. Mooney V, McDermott KL, Song J: Effects of smoking and maturation on long-term maintenance of lumbar spinal fusion success. J Spinal Disord 1999; 12:380�5.
32. Flood P, Ramirez-Latorre J, Role L: Alpha 4 beta 2 neuronal nicotinic acetylcholine receptors in the central nervous system are inhibited by isoflurane and propofol, but alpha 7-type nicotinic acetylcholine receptors are unaffected. ANESTHESIOLOGY 1997; 86:859�65.
33. Moller AM, Villebro N, Pedersen T, Tonnesen H. Effect of preoperative smoking intervention on postoperative complications: a randomized clinical trial. Lancet 2002; 359:114-117.
34. Sorensen LT, HorbyJ, Friis E, Pilsgaard B, Jorgensen T: Smoking as a risk factor for wound healing and infection in breast cancer surgery. EurJ Surg Oncol 2002; 28:815�20
35. Chang, D. W., Reece, G. P., Wang, B., Robb, G. L., Miller, M. J., & Evans, G. R. D. et al. (2000). Effect of smoking on complications in patients undergoing free TRAM flap breast reconstruction, Plastic and Reconstructive Surgery, 105, 2374-2380.
36. Netscher DT, Clamon J. Smoking: adverse effects on outcomes for plastic surgical patients. Plast Surg Nurs 1994;14(4):205-10.
37. Myles PS, Iacono G, Hunt JO, et al. The risk of respiratory complications and wound infection in patients undergoing ambulatory surgery: smokers versus nonsmokers. Anesthesiology 2002; 97: 842-847.
38. Benowitz NL, "Biomarkers of Environmental Tobacco Smoke Exposure," Environ Health Perspect 107 Suppl 2: 349-55, 1999.
39. Pojer R, Whitfield JB, Poulos V, Eckhard IF, Richmond R, Hensley WJ. Carboxyhaemoglobin, cotinine and thiocyanate assays compared for distinguishing smokers from non-smokers. Clin Chem 1984; 30:1377-1380.
40. Jarvis MJ, Tunstall-Pedoe H, Feyerabend C, Vesey C, Saloojee Y. Comparison of tests used to distinguish smokers from non-smokers. Am J Public Health 1987; 77:1435-1438.
41. Boffa, J. A comparison of three methodologies to detect the presence of cotinine in urine. International Colloquium on Prospective Biology. Nancy France 1988.
42. Fitzpatrick J. Urinary Cotinine Clin Chem News 1991; 11. Fitzpatrick J, Lenda R. Chromatographic immunoassay device and method utilizing particle valency for quantitation. PCT/US97/05077.
43. Jacob,III, P. and Byrd, G.D. "Use of gas chromatographic and mass spectrometric techniques for the determination of nicotine and metabolites." pp 191-224. In Analytical Determination of Nicotine and Related Compounds and Their Metabolites: Ed Gorrod, J.W. and Jacob III, P.Elsevier 1999.
44. Bernert J.T., Turner W.E., Pirkle J.L., et, al Development and measurement of a sensitive measurement of serum cotinine in both smokers and non-smokers by liquid chromatography / atmospheric pressure ionization tandem mass spectrometry. Clin. Chem. 1997; 43:2281-2291.



